Common Use

This anti-tuberculosis medication has a bacteriostatic effect, suppressing bacterial protein synthesis. It inhibits the growth and spread of tuberculosis mycobacteria both inside and outside cells. Ethionamide also enhances phagocytosis at tuberculosis inflammation sites, aiding resolution. It may also be used to treat leprosy (Hansen's disease).

Dosage and Directions

Your doctor will determine the correct dose based on your condition, age, and weight. Take with a full glass of water, with or without food. Taking Ethionamide with food may help prevent stomach upset. Continue treatment as prescribed, even if symptoms disappear, to ensure complete eradication of infection. Only stop taking this medication under medical supervision.

Precautions

• Inform your doctor about all medications and herbal supplements you are taking.
• Disclose any allergies or medical conditions.
• Notify your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Contraindications

• Severe liver impairment
• Hypersensitivity to Ethionamide
• Pregnancy

Use with caution in patients with diabetes or epilepsy.

Possible Side Effects

• Allergic reactions (rash, hives, facial swelling)
• Gastrointestinal issues (nausea, vomiting, diarrhea, abdominal pain)
• Jaundice or loss of appetite
• Stomatitis
• Nervous system effects (peripheral neuritis, confusion, depression)
• Coordination problems and numbness/tingling in extremities
• Menstrual irregularities and impotence

Contact your doctor immediately if you experience severe or persistent side effects.

Drug Interactions

Ethionamide may interact with:

• Cycloserine and isoniazid
• Sedatives and tranquilizers
• Sleep medications
• Narcotic pain relievers
• Certain antidepressants (e.g., amitriptyline)
• Antihistamines (e.g., diphenhydramine)

The drowsiness effect may be intensified when combined with these drugs. Concurrent use with other anti-tuberculosis medications may increase seizure risk.

Missed Dose

Take the missed dose as soon as you remember. If it's almost time for the next dose, skip the missed dose. Never double your dose to compensate.

Overdose

Symptoms of overdose are not well documented. Seek immediate medical attention if you suspect an overdose.

Storage

• Store at room temperature (59-77°F or 15-25°C)
• Keep away from light and moisture
• Store out of reach of children and pets

Disclaimer

This information provides a general overview and does not cover all possible uses, interactions, or precautions. Always consult your healthcare provider for personalized medical advice. Do not use this information for self-diagnosis or self-treatment. We are not liable for any consequences resulting from the use of this information.