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Manufacturer: Cipla Limited, Glenmark Pharmaceuticals Ltd., Intas Pharmaceuticals Ltd., Zydus Cadila Healthcare
Diseases caused by pathogens that require intensive drug therapy. For the treatment often used a medication such as Levofloxacin.

Levofloxacin is the optically active isomer of Ofloxacin. He also is called L-ofloxacin. Has a wide range of antibacterial effects. The tool is a stopper topoisomerase and DNA gyrase bacteriophagy.

The drug disrupts the flow of superspiralizatiou and binding of DNA breaks, is provoking profound morphological changes in the cell wall of the microbe, its membranes and the cytoplasm. If you are using doses that are similar to or exceed the minimum inhibiting concentration, it is bactericidal effect. Levofloxacin is active against almost all microorganisms.

To remedy such sensitive pathogens: golden and epidermal staphylococci, faecal enterococci, pneumococcus, saprophytic Staphylococcus aureus, pyogenic Streptococcus including m-multidrug-resistant, Klebsiella pneumonia, Serratia marcescens, Pseudomonas aeruginosa, Enterobacter cloacal, Proteus mirabilis, E. coli, Moraxella of catarhalis, Haemophilus coli, Legionella of pneumophila, Haemophilus influenzae, coli — gram-negative.

A list of sensitive to Levofloxacin pathogens is much more. Fully resistant to its effects: anaerobic, bacteria thetaiotaomicron, aerobic gram-negative, Alcaligenes xylosoxidans, is an aerobic gram-positive staphylococci, the coagulate-negative methi-R Staphylococcus aureus methi-R.

With the consumption of 500 mg of the drug inside at a halt-life time means is equal to 7-8 hours, excreted mainly by the kidney through glomerular filtration and secretion in the tubules. In the form of metabolites excreted kidneys are no more than 5% of the funds. Pharmacokinetics is the same in humans of different age and sex.

The drug is usually prescribed for appearance of viral and infectious diseases that are caused by exposure to viral and bacterial organisms. Such pathologies include: bronchitis acute and chronic, acute sinusitis, bacterial prostate, infectious lesions of the skin or soft tissue, pneumonia, septicemia or bacteremia, intraabdominal infections, infections of the genitourinary system different neglect (such as pyelonephritis), drug resistant forms of tuberculosis.

Technical Information

Brand names: Cravit, Elequine, Floxel, Iquix, Leroxacin, Lesacin, Levokacin, Levox, Levoxacin, Mosardal, Nofaxin, Quixin, Reskuin, Tavanic, Volequin
Imprints: Levaquin (levofloxacin) LEVAQUIN 500, Levaquin (levofloxacin) LEVAQUIN 750, Levaquin (levofloxacin) LEVAQUIN 250

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